PET Radiochemistry
Main objective of our PET radiochemistry research is development of new radiosynthetic methods and radiolabeling technologies for development of new PET tracer candidates and for facilitating production of PET radiopharmaceuticals for clinical use. We also continuously develop automated radiosynthetic instrumentation and procedures and new quality control and radiometabolite analysis methods for promoting clinical translation of new PET radiopharmaceutical candidates. PET radiochemistry research has long traditions at TPC, during which several new PET tracer candidates have been successfully translated from preclinical to clinical phase.
Some of our current research topics include development of new methods for bioorthogonal and transition metal- and photocatalyzed radiochemistry for synthesis of 15O-, 11C- for 18F-labelled compounds and development and investigation of new radiopharmaceuticals for PET imaging of inflammation and cancer, and metabolic and neurological diseases. The development and evaluation of new PET tracer candidates is made in close cooperation with the TPC preclinical imaging unit (see preclinical imaging unit) and translation to clinical production together with our Radiochemistry GMP production personnel (see radiochemistry core facility).
Meet our experts
